During 1817/18 Dillis accompanied Crown Prince Ludwig of Bavaria on a trip through Italy, which extended as far as Sicily. On their way back they stayed for three months in Rome in the Villa Malta that Ludwig was to take possession of a few years later. It was there that the famous Roman views (in the Schack-Gallery, Munich) were painted, in which Dillis captured the city view from the Villa Malta in hazy morning light. The Neue Pinakothek's "View from of the Quirnal from Villa Malta" was most probably painted around the same time as the three views in the Schack Gallery. The painting was not so much conceived as a veduta, but rather to capture the character of the Villa Malta, residence of the Crown Prince and his circle of friends.
For his painting Dillis chose an unusual and pleasant view: The foreground integrates the villa's rooftop terrace, which extends to the back with a pergola entwined with ivy. The pergola acts as an inner frame and creates a kind of box that concentrates the view of the city, which lies far in the distance. Through the placement of a bench and a statue, the terrace is marked as a private area and furthermore, through a subtle use of light falling through the roof of leaves, intensifies the intimacy of the setting.