Emotional proximity rather than reverential distance mark the atmosphere in this sacra conversazione. The Virgin Mary hands over her son, who God sent to the world for the redemption of mankind, representationally, to John the Baptist who accepts him with a tender gesture. John was probably the namesake of the unknown donor who is kneeling close to the Mother of God. The inclusion of his portrait in the scene signifies everlasting veneration and guarantees that he will be remembered forever (memoria).